BBB Dysfunction Study by Ischemia-Reperfusion Injury Model | Protocol Preview

Описание: Watch the Full Video at https://www.jove.com/v/52699/oxygen-g....

Oxygen-Glucose Deprivation and Reoxygenation as an In Vitro Ischemia-Reperfusion Injury Model for Studying Blood-Brain Barrier Dysfunction - a 2 minute Preview of the Experimental Protocol

Himakarnika Alluri, Chinchusha Anasooya Shaji, Matthew L. Davis, Binu Tharakan
Texas A&M University Health Science Center College of Medicine, Department of Surgery; Baylor Scott & White Health, Department of Surgery;

Ischemia-Reperfusion (IR) injury is associated with a high rate of morbidity and mortality. The goal of the in vitro model of oxygen-glucose deprivation and reoxygenation (OGD-R) described here is to assess the effects of ischemia reperfusion injury on a variety of cells, particularly in blood-brain barrier (BBB) endothelial cells.

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