Lecture On Anemia & Polycythemia: Classification, RBC Indices (MCV, MCH, MCHC) | MBBS

Описание: This session provides a comprehensive physiological analysis of red blood cell disorders, focusing on diagnostic parameters and clinical classifications that are essential for medical examinations and clinical practice.

What You Will Learn:

Definition of Anemia: Moving beyond simple low hemoglobin to understanding tissue oxygen demand and physiological needs [04:21].

RBC Indices (MCV, MCH, MCHC): Step-by-step mathematical derivation of mean corpuscular volume, hemoglobin content, and concentration—essential for lab diagnosis [11:19].

Morphological Classification: Differentiating between Microcytic Hypochromic (Iron Deficiency), Macrocytic (Vitamin B12/Folate deficiency), and Normocytic Normochromic anemias [26:40].

Etiological & Functional Classification: Exploring causes from blood loss (hemorrhagic) to increased destruction (hemolytic) and production failures (aplastic anemia) [38:12].

Reticulocyte Count: Using "retic counts" to identify bone marrow compensation and distinguish between hemolytic and chronic disease anemias [33:17].

Polycythemia: Understanding Absolute vs. Relative polycythemia, Polycythemia Vera (Rubra Vera), and secondary causes like high-altitude adaptation [53:26].

Physiological Basis of Treatment: Key principles in managing anemia, including ensuring tissue oxygen delivery and treating underlying causes like Chronic Kidney Disease (CKD) [51:44].

Key Timestamps:

[00:21] – Defining Anemia: Hemoglobin vs. Tissue Oxygen Demand

[06:49] – Factors influencing RBC counts (Age, Sex, Altitude)

[11:19] – Understanding RBC Indices: MCV, MCH, and MCHC explained

[15:30] – How to calculate MCV from Hematocrit (PCV)

[21:21] – MCHC: Why "Hyperchromic" is a rarely appropriate term

[26:40] – Morphological Classification: Microcytic vs. Macrocytic

[27:47] – Nutritional Anemias: Iron vs. B12/Folate Deficiency

[31:19] – Aplastic Anemia & Bone Marrow Failure

[36:50] – Causes of Anemia: From Blood Loss (PPH) to Hookworm Infection

[43:40] – Anemia in Chronic Kidney Disease: The role of Erythropoietin

[51:44] – Physiological Principles of Anemia Management

[53:26] – Polycythemia: Classification and Pathophysiology

[55:30] – Polycythemia Vera (Rubra Vera) Explained


SANTINIKETAN MEDICAL COLLEGE & HOSPITAL
Real Classroom Demonstration/Lecture
On: PHYSIOLOGY by Dr. Akash Ghosh Roy
(MBBS Batch: 2025-26)
Conducted on: 11-02-26