Rate-Limiting Enzymes and Their Regulation | MCAT

Описание: TL;DR: The rate-limiting enzyme of any metabolic process is the enzyme that catalyzes the slowest, or rate-limiting, step of that metabolic process. Its regulation is specifically important because it determines not just the rate of that specific reaction, but the rate of the overall metabolic process.

Today’s MedCat video covers the different rate-determining (aka rate-limiting) enzymes of glycolysis, the Krebs cycle [aka Citric Acid Cycle (CAC) or Tricarboxylic Acid Cycle (TCA Cycle)], gluconeogenesis, glycogenesis, glycogenolysis, and the pentose-phosphate-pathway [aka hexose-monophosphate shunt (HMP shunt)]. All of these enzymes (listed below) are covered with their major substrates, coenzymes, and cofactors, as well as their relevant regulators.

Phosphofructokinase-1 (PFK-1)
Isocitrate dehydrogenase
Fructose-1,6-bisphosphatase
Glycogen synthase
Glycogen phosphorylase
Glucose 6-P dehydrogenase (G6PDH or G6P dehydrogenase)

Time Stamps:
Intro: (0:00)
What Is a Rate-Limiting Enzyme?: (0:08)
Rate-Determining Enzymes: (1:52)
Regulation of Rate-Determining Enzymes: (8:15)
Outro: (13:03)

Comprehensive Amino Acid Playlist: https://bit.ly/3sMGBUG
Check out Aratasaki, the beat maker behind my intro and outro: https://bit.ly/2Pma5v0
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All content and media on this channel is created and published online for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice.
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#mcat #ratelimitingenzymes #enzymeregulation
Rate-Limiting Enzymes and Their Regulation | MCAT
Rate-Limiting Enzymes and Their Regulation | MCAT
Rate-Limiting Enzymes and Their Regulation | MCAT