PHARMACOLOGY SAQ22: LA TOXICITY

Описание: 00:00 20mls of 0.5% bupivacaine is inadvertently administered intravenously over 15 seconds to a 60 year old, 60kg woman.
(a)  Describe the potential complications and mechanisms of these. (6marks)
4:13 (b)  Briefly outline the acute management of the potential complications. (4 marks)

6:09 Determinants of local anaesthetic systemic toxicity (LAST)
9:33 Other examples of LA toxicity apart from LAST
10:39 Intralipid 20%
12:46 Mechanism of action of LAs

Suggested reading:
Pharmacology for Anaesthesia and Intensive Care. 4th edition. 2014. Author: Tom E. Peck & Sue A. Hill. Publisher: Cambridge University Press

Principles and Practice of Pharmacology for Anaesthetists. 5th edition. 2008.
Author: Norman Calvey & Norton Williams Publisher: Wiley-Blackwell

Pharmacology short notes and summary tables for primary anaesthesiology exams. 2nd edition. 2022. Author: Leong Kok Weng. Publisher: HKL.

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