Lossen rearrangement | Organic Chemistry | Urdu / Hindi
Автор: Chem club
Загружено: 2020-12-17
Просмотров: 885
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Video Title: Lossen Rearrangement
Description:
Welcome to Chem Club! I’m Imran Mughal, and in this video, we’ll be exploring the Lossen Rearrangement, an important reaction in organic chemistry used to convert amides into isocyanates or amines via a rearrangement process.
In this video, you’ll learn about:
What is the Lossen Rearrangement?: Understand the basics of the Lossen rearrangement, a reaction in which amides are converted into isocyanates or amines through the action of a base or acid.
The Mechanism of the Lossen Rearrangement: Dive into the step-by-step mechanism, starting with the deprotonation of the amide, followed by the formation of a cyclic intermediate, and the final rearrangement to form the isocyanate or amine.
Reaction Conditions: Learn about the conditions required for the Lossen rearrangement, including the use of a strong base like sodium hydroxide (NaOH) or an acid catalyst, and how these conditions affect the reaction pathway.
Applications of the Lossen Rearrangement: Discover how the Lossen rearrangement is applied in organic synthesis to form valuable compounds like isocyanates, which are used in the preparation of polyurethane foams and other chemicals.
Limitations and Variations: Understand the challenges and variations in the Lossen rearrangement, such as the choice of reactants, solvents, and catalysts, which can influence the outcome of the reaction.
This video is ideal for organic chemistry students and researchers who are looking to understand this important rearrangement and its role in chemical synthesis.
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