Virology Lectures 2021 #21 - Evolution

Описание: Viral evolution, the change of a viral population in the face of selection pressures, occurs faster than in other organisms because viruses produce so many progeny harboring many genome mutations. In this lecture we consider the four main drivers of viral evolution: large numbers of progeny, mutation, selection, and quasispecies effects. We discuss selection by the immune system and how it gives rise to antigenic drift and antigenic shift in the context of influenza viruses and SARS-CoV-2. We conclude by a review of the origins of viruses in the pre-cellular world and why all viruses emerge not de novo, but from existing viruses.

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