Why Energy Supplements Stop Working After 45 | Dr. David Sinclair Reveals the Hidden Aging Mechanism

Описание: Why do energy supplements that once worked perfectly suddenly feel useless after age 45? In this episode, Dr. David Sinclair explains the real science behind age-related energy decline and why most popular energy supplements stop delivering results as we get older. This is not about motivation, willpower, or taking higher doses — it’s about how aging changes your cells, mitochondria, and energy-producing pathways.

As we age, our mitochondria become less efficient, NAD levels drop, insulin sensitivity declines, and chronic inflammation increases. These changes silently block the way energy supplements work. Dr. Sinclair breaks down how cellular signaling shifts after midlife, why stimulants backfire, and why “more supplements” is often the worst solution.

In this video, you’ll learn why caffeine and B-vitamins fail after 45, how mitochondrial dysfunction drives fatigue, why NAD is critical for real energy, and what actually restores long-lasting energy instead of short-term stimulation. This is cutting-edge longevity science explained simply, clearly, and backed by biology.

If you’re tired of energy crashes, brain fog, and supplements that no longer work, this video will change how you think about energy, aging, and longevity forever.

⏱ TIMESTAMPS:

00:00 – Why energy supplements stop working after 45
01:28 – The biggest myth about energy and aging
03:02 – What really creates energy inside your cells
04:47 – Mitochondria and age-related fatigue
06:19 – Why caffeine and stimulants backfire after midlife
07:58 – NAD decline and cellular energy loss
09:36 – Insulin resistance and energy crashes
11:02 – Why more supplements make fatigue worse
12:34 – The difference between stimulation vs restoration
14:01 – How real energy is rebuilt after 45
16:10 – The future of energy and longevity science

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