Anthelmintic Drugs | Mebendazole and Albendazole Pharmacology and Mechanism of Action-HINDI- Part-2

Описание: Anthelmintics are drugs that are used to treat infections with parasitic worms. This includes both flat worms, e.g., flukes and tapeworms and round worms, i.e., nematodes. They are of huge importance for human tropical medicine and for veterinary medicine.
In this lecture we discuss about two drugs -
1. Albendazole – effective against threadworms, whipworms, tapeworms, hookworms, roundworms,
2. Mebendazole – effective against various types of nematodes

MCQ of Lecture based on Mebendazole and Albendazole Pharmacology
Q. 1 Mechanism of action of Mebendazole is
A. It block glucose uptake in worm
B. It Bind to GABA receptor & Hyperpolarize the worm muscle
C. Bind to beta Tubulin of worm and inhibit polymerization
D. A & C

Q. 2 Mechanism of action of Albendazole is
A. It activate Nicotinic Receptor
B. It Bind to GABA receptor & Hyperpolarize the worm muscle
C. Sulfone metabolite of albendazole Bind to beta Tubulin of worm and inhibit polymerization
D. It act through Glutamate ion channel

Q. 3 Side effect of Mebendazole is
A. Loss of Hair
B. Granulocytopenia
C. Both
D. None

Q. 4 Choose INCORRECT statement
A. Mebendazole is more active than albendazole for strongyloidosis
B. Mebendazole is Less active than albendazole for Hydatids
C. Mebendazole is More active than albendazole for Hook Worms
D. Metabolite of Albendazole is active

Q. 5 For which infections albendazole is given with fatty meal
A. Cystecercosis
B. Hydatids
C. Both
D. None

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