Jonathan Epstein - mRNA-mediated Immunotherapy for Heart Failure

Описание: This presentation, presented on Friday, December 10th, 2021 was part of the sixth annual 2021 Ted Rogers Centre Heart Failure Symposium.

The sixth annual Ted Rogers Centre Heart Failure Symposium was held virtually from December 10-11, 2021. This meeting, which blends clinical innovations with the latest scientific advances, has grown to become Canada’s largest conference on heart failure.

On Friday, December 10th, our research-focused symposium examines congenital heart disease, and how we can take animal models and regenerative medicine approaches to answer the clinical challenges that remain. It also highlights commercialization success stories, and sees how innovators developed an idea and translated it to impact. And it will shine a light on unique new scientific approaches in the emerging field of cardiotoxicity.

About the speaker:
Jonathan Epstein, MD, is the William Wikoff Smith Professor, executive vice dean and chief scientific officer at the Perelman School of Medicine at the University of Pennsylvania, and senior vice president and chief scientific officer at the University of Pennsylvania Health System. His research has focused on the molecular mechanisms of cardiovascular development and implications for understanding and treating human disease. His group has been at the forefront of utilizing animal models of congenital heart disease to determine genetic and molecular pathways required for cardiac morphogenesis, with implications for pediatric and adult cardiovascular disease. Stem cell, angiogenesis and epigenetic studies have had direct implications for the development of new therapeutic agents for heart failure and myocardial infarction.

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