Challenges Faced in Pregnancy with Advanced Maternal Age

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Dr Sweta Gupta Explaining Advanced Maternal Age

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Video Transcript

One of the factors that should be considered while planning pregnancy is the maternal age. Because with advanced maternal age the fertility of a woman declines, especially after mid- 30’s, and if she conceives it would be a high-risk pregnancy.

Q) What is advanced maternal age? 0:33

A) Advanced maternal age (AMA) or advanced reproductive age is defined as women who conceive when they are 35 years or older. With advanced age, there is a trend of decreasing fertility, as the quality and quantity of eggs deteriorate. A woman not only finds it difficult to get pregnant, but the chances of miscarriage also increase.

Q) What are the risks associated with advanced maternal age? 0:59

A) • A female is born with a fixed number of eggs, and as she ages the number of eggs available significantly decreases, thus reducing fertility.
• With age egg quality deteriorates and there is an increased chance of chromosomal activities like down syndrome and chances of miscarriage
• In addition, it is common to find uterine fibroids and endometrial polyps in older women which in a way can also affect a woman’s fertility.

Q) What can be done to increase the chances of pregnancy? 1:38

A) To increase the chances of pregnancy in older women we recommend them
• To lead a healthy lifestyle, reduce stress and start with prenatal vitamins.
• Counselling the patient on the awareness of the effect of age on fertility is essential
1) As a woman who is older than 35yrs should receive evaluation and treatment after 6 months of failed attempts to conceive.
2) And in women older than 40yrs, immediate evaluation and treatment is needed
• Get a pre-conception check-up, and a detailed family history is asked. If during investigations Hypertension, diabetes, thyroid disorders are found, they should be managed well medically, as these can lead to a high-risk pregnancy.

Q) What are the treatment options for advanced age woman? 2:34

A) • The chances of natural pregnancy at an age of 35 starts declining, and by the time a woman is 40, it falls steeply. But with assisted reproductive techniques the chances of a successful pregnancy increases.
• After a brief period of ovulation induction, IVF is the recommended choice. IVF can make the optimal use of the limited eggs left in the ovary provided the matured egg retrieved in a specific IVF cycle is of good quality.
• And for women for whom ovarian stimulation to retrieve good quality eggs have failed, then IVF with a donor egg should be considered where a donor egg of younger age group woman is taken with matching the profile and donor egg is mixed with husband's sperm and a good quality embryo is formed. Donor egg IVF treatment can be helpful in women who have had their menopause and can make them pregnant also.

Q) How can Medicover Fertility help women to conceive in their advanced age? 3:46

A) Medicover fertility clinics are among the top fertility clinics in Europe now in India. With state-of-the-art technology and technical expertise of doctors, we have been helping older women with planning a pregnancy.
Motherhood now does not have to be limited to the younger women only. Advances in fertility treatments have helped many older women to conceive successfully and have babies under our guidance.

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