How to use MULTI-Evolve to design proteins with machine learning

Описание: Vincent Tran of the Patrick Hsu Lab walks through the UI for MULTI-evolve, a machine learning-guided end-to-end framework for engineering hyperactive multi-mutant proteins. It is open source on Github and can be used in your browser.

GitHub Link: https://github.com/ArcInstitute/MULTI...

About the Speaker:
Vincent Tran (X: @tranvinq) is a postdoctoral researcher in the Hsu lab. He received his PhD from the University of California, Berkeley in 2024.

Paper Citation:
Tran, V.Q., Nemeth, M., Bartie, L.J., Chandrasekaran, S.S., Fanton, A., Moon, H.C., Hie, B.L., Konermann, S., & Hsu, P.D. (2026). Rapid directed evolution guided by protein language models and epistatic interactions. Science. https://doi.org/10.1126/science.aea1820