What Drugs Cause Dilated Pupils?

Описание: Few people take drugs to change the way their eyes look. For most people who misuse drugs, changed pupil size is a side effect.

The pupils may dilate more with certain types of drugs and higher doses. Some people are also more susceptible to this effect.

Substances that can cause dilated pupils include the following:

Illicit drugs, such as bath salts, MDMA, LSD, mescaline, and methamphetamine

Prescription drugs, such as amphetamines, antidepressants, benzodiazepines, ketamine, muscle relaxants, and stimulants
Over-the-counter drugs, such as decongestants and nicotine

Every drug in this list has a unique chemical makeup, and they all work on your body in different ways. Drugs can dilate your pupils due to the following reasons:

Nervous system depression: Medications like muscle relaxants aren’t targeted. If one muscle slackens, all of them do. Anything that can cause relaxation or slowed reflexes could work on the muscles in your eye and make your pupils widen.

Dopamine release: Some drugs cause brain cells to release large amounts of the feel-good chemical dopamine. Your pupils widen in response to natural dopamine, which is why your eyes seem to widen when you see someone you love. An artificial dopamine release can cause pupil changes in the same way.

Unknown mechanism: Street drugs have all sorts of additives and chemicals, and some haven’t been studied by experts. We don’t really know what’s in every dose of bath salts, for example. Those substances could widen pupils, but we don’t know why.

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