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KB707-02: inhaled KB707 for lung-related advanced solid tumors

Speaker: Wen Wee Ma

Institution: Cleveland Clinic Taussig Cancer Institute

Event: ASCO 2025

Format: Interview

Subject: General

Subject: Non-Small Cell Lung Cancer

Subject: Lung Cancer

Trial: KB707-02

NCT06228326

Field: Immuno-Oncology

Medicines: KB707

Medicines: Pembrolizumab

Medicines: Antibodies

Medicines: Checkpoint inhibitors

Автор: VJOncology

Загружено: 2025-06-04

Просмотров: 85

Описание: Wen Wee Ma, MBBS, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH, safety and preliminary efficacy findings from the Phase I/II KB707-02 study (NCT06228326), evaluating inhaled KB707 monotherapy in patients with advanced solid tumors involving the lungs. KB707, a herpes simplex virus–based vector encoding IL-12 and IL-2, demonstrated a favorable safety profile with no severe treatment-related toxicities. The study has now expanded to assess combination strategies with pembrolizumab for non-small cell lung cancer. This interview took place during the 2025 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.

These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.

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KB707-02: inhaled KB707 for lung-related advanced solid tumors

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