Plasma pTau181 and pTau217 predict asymptomatic amyloid accumulation equally well as amyloid-PET
Автор: BRAIN Journals
Загружено: 2025-06-30
Просмотров: 262
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Read the full article: https://academic.oup.com/braincomms/a...
The dynamic phase of preclinical Alzheimer’s disease, as characterized by accumulating cortical amyloid-β, is a window of opportunity for amyloid-β–lowering therapies to have greater efficacy. Biomarkers that accurately predict amyloid-β accumulation may be of critical importance for participant inclusion in secondary prevention trials and thus enhance development of early Alzheimer’s disease therapies. We compared the abilities of baseline plasma pTau181, pTau217 and amyloid-β PET load to predict future amyloid-β accumulation in asymptomatic elderly.
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