Zolbetuximab, Immunotherapy Combinations, and the Future of Upper GI Targeting
Автор: OncUpdates: Latest Oncology Insights
Загружено: 2026-01-24
Просмотров: 1193
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Join us in this insightful episode of our podcast as we dive into the latest advancements in gastrointestinal oncology with Dr. Shruti Patel from Stanford and the VA Palo Alto, and Dr. Timothy Brown from UT Southwestern in Dallas, Texas.
In this episode, we discuss the promising new trials surrounding Zolbetuximab, particularly its role in treating esophageal and gastric cancers. We explore the findings from the recent ASCO-GI conference, including the encouraging results from the Ilustra trial, which examined the combination of Zolbetuximab with chemotherapy and Nivolumab in patients expressing Clon-18.2.
We also address the challenges of toxicity associated with Zolbetuximab, especially in patients with upper GI cancers, and how these factors may influence clinical decisions. Additionally, we touch on the potential of Clon-18.2 as a target for CAR T-cell therapy in solid tumors, highlighting exciting developments from recent studies.
Tune in to learn more about the future of GI cancer treatment and the evolving landscape of targeted therapies!
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#GIOncology, #Zolbetuximab, #CLDN182, #ASCOGI, #CARTcellTherapy
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