The Gut-Immune Brain Axis: Nutritional Approaches to Neuroinflammation

Описание: In this edition of the Research Seminar Series, Dr. Annie Lin shares her research on the gut-immune brain axis. Her work is presented through a systems-level framework that integrates the roles of the microbiome, immune signaling, mitochondrial function, and their collective impact on brain health.

Dr. Lin highlights common mechanisms underlying many chronic illnesses and how they are interconnected through the immune-brain axis. She further explores practical, nutrition-based interventions aimed at modulating these pathways, emphasizing the critical role of dietary and lifestyle changes in shifting health outcomes.

By applying a systems biology perspective, Dr. Lin examines how dysregulation in these interconnected systems contributes to inflammation and symptoms, including oral-systemic inflammation.

Key Points:
00:00 Introduction
02:46 Neuroinflammations as the unifying thread
04:43 Common symptoms among chronic illnesses
06:56 Systems biology approach to symptoms
08:54 The gut-immune brain axis
10:45 Disruption in pathways drives chronic symptoms
11:45 Dysbiosis increases gut permeability
13:15 Gut-immune brain access dysregulation
16:07 Clinical significance of the gut-immune brain axis
17:55 Modulating neuroinflammation through nutrition
20:13 Reviews published for gut-brain axis
23:16 Practical ideas to support fatigue
24:08 Gut health begins in the mouth
25:19 Digestive and immune system frontline: Mouth
26:37 Oral inflammation and systemic outcomes
28:08 Interventions for oral systemic inflammation
30:29 The role of microglia as pro-inflammatory responders
33:22 Microglia exposed to inflammatory triggers
35:05 Migcroglia locked in defense mode
35:52 Calming microglia activation
36:53 Metabolic shift through fasting
37:32 Mitochondria’s role in inflammation and brain health
39:15 Effects of mitochondrial dysfunction
41:03 Nutrients for mitochondrial energy production
42:07 Lifestyle and behavioral modulation
43:06 Fasting, hydration, and proper nutrition
44:19 Mitochondria’s role in energy and pain regulation
48:16 Nutrition and mitochondrial health
49:53 Individualized care focused on nutrition
53:26 Nutrition with genomics and microbiome science
54:54 Microbial metabolites as biomarkers
56:22 Future of work

Dr. Annie Lin is a Licensed and Board-Certified Nutrition Specialist focusing on integrative and functional nutrition approaches for optimizing health and addressing root causes of clinical imbalances. She is a dedicated assistant professor in the Department of Nutrition, teaching a variety of courses including functional nutrition in the graduate program. With a doctorate in Clinical Nutrition from Maryland University of Integrative Health and training from the Institute for Functional Medicine, she combines academic rigor with practical expertise in using Food as Medicine.

LinkedIn:  / annielin1  

Learn more about the Institute for Neuro-Immune Medicine here.

Website: https://www.nova.edu/nim/
Facebook:   / instituteforneuroimmunemedicine  
Instagram:   / nsu_inim  
Twitter:   / nsu_inim  


#Neuroinflammation #GutBrainAxis #FunctionalMedicine