Analytical Ultracentrifugation - Stephen McLaughlin

Описание: The LMB Biophysics Facility houses a wide range of state-of-the-art and in-house built instruments that enable the molecular characterisation of macromolecular size, shape, mass, stability, binding affinity, dynamics and interaction kinetics.

The facility is primarily intended for hands-on research by students, postdocs, and group leaders, who prepare samples and make measurements. Biophysics supports users in advice on experimental techniques and results, training and in collaborative research.

In this video Stephen explains the physical principles that underlie analytical ultracentrifugation (AUC). He describes the different type of experiment, detection systems, sample requirements and how data is analysed to investigate the mass, shape and interactions of sedimenting particles. He gives examples of how AUC has been employed in a variety of projects. In addition, he shows how recent methods have been applied to the analysis of glycoproteins and membrane proteins.

The Biophysics Facility is headed by Chris Johnson, supported by Stephen McLaughlin.

Read more about the facility here: https://www2.mrc-lmb.cam.ac.uk/resear...

You can find more videos from the LMB 2021 Biophysics Techniques Lecture series here:
   • Introduction to Biophysical Techniques 2021  

Other playlists you might be interested in:
Next Generation Biophysics Symposium 2020 -    • Next Generation Biophysics Symposium 2020  
Electron Cryo-Microscopy Course 2017 -    • Electron Cryo-microscopy Course 2017  
RNA Seq Course -    • RNA-seq Course 2020  
LMB Crystallography Course 2013 -    • LMB Crystallography Course 2013  

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