SPINDLE CELL UNKNOWNS | Bone & Soft Tissue Pathology Cases for Residents |

Описание: Digital Slides:
Case 1: https://kikoxp.com/posts/26465
Case 2: https://kikoxp.com/posts/26467
Case 3: https://kikoxp.com/posts/26469

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Additional Cases:
CASE 1:
Schwannoma Variants:
Antoni A Predominant: https://kikoxp.com/slides/public/647a...
“Zebra Stripe” Verocay Bodies: https://kikoxp.com/slides/public/647a...
Cellular Features: https://kikoxp.com/slides/public/647a...
Extensive Hyalinization: https://kikoxp.com/slides/public/647a...
Extensive Myxoid Change: https://kikoxp.com/slides/public/647a...
Round Cell Features: https://kikoxp.com/slides/public/647a...

CASE 2:
Hyalinizing spindle cell tumor with giant rosettes (LGFMS variant): https://kikoxp.com/slides/public/647e...
Myxofibrosarcoma, high-grade: https://kikoxp.com/slides/public/6482...

CASE 3:
Post-Treatment Synovial Sarcoma: https://kikoxp.com/slides/public/647e...
Metastatic Synovial Sarcoma: https://kikoxp.com/slides/public/647e...
Metastatic Leiomyosarcoma: https://kikoxp.com/slides/public/647e...
MPNST/Malignant Triton Tumor: https://kikoxp.com/slides/public/647e...

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References:
1. Casadei GP, Scheithauer BW, Hirose T, Manfrini M, Van Houton C, Wood MB. Cellular schwannoma. A clinicopathologic, DNA flow cytometric, and proliferation marker study of 70 patients. Cancer. 1995;75(5):1109-1119. https://pubmed.ncbi.nlm.nih.gov/7850709
2. Schaefer IM, Hornick JL. SWI/SNF complex-deficient soft tissue neoplasms: An update. Semin Diagn Pathol. 2021;38(3):222-231. https://pubmed.ncbi.nlm.nih.gov/32646614
3. Zaborowski, M.; Vargas, A.C.; Pulvers, J.; Clarkson, A.; de Guzman, D.; Sioson, L.; Maclean, F.; Chou, A.; Gill, A.J. When used together SS18-SSX fusion-specific and SSX C-terminus immunohistochemistry are highly specific and sensitive for the diagnosis of synovial sarcoma and can replace FISH or molecular testing in most cases. Histopathology 2020, 77, 588–600. https://pubmed.ncbi.nlm.nih.gov/32559...

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Note: This video is for educational purposes only and is not formal medical advice or consultation.