ADME 101 Guide to Subcellular Fractions and When to Use Which Test System

Описание: Originally aired: May 2020
Presenter: Chris Bohl, Ph.D., Global Technical Support Manager

This ADME 101 video provides an overview of different types of subcellular fractions, such as microsomes, S9, cytosol, lysosomes and homogenate, and their unique benefits for use in various types of in vitro ADMET/DMPK & Drug-Drug Interaction studies. This short, information-packed webinar features:

The different types of subcellular fractions
How they are made
Who uses them, for which studies, and why
Advantages of the test systems
Different preparation options
Whether to use a NADPH regenerating system or 1mM NADPH
How tissue is procured and more...

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About the presenter: Dr. Chris Bohl received his PhD from the School of Biological Sciences from the University of Nebraska – Lincoln and has been with XenoTech since 2014, first operating as a research scientist before becoming the Senior Manager of Technical Support for Products.