Immune Thrombocytopenia (ITP) — Most COMPREHENSIVE Explanation — Hematology

Описание: Immune Thrombocytopenic Purpura (ITP) (aka Idiopathic Thrombocytopenic Purpura or immune thrombocytopenia)…autoimmune attack on platelet receptors leading to bleeding (petechiae, purpura,and ecchymosis)…Order bleeding time, platelet count, PT, and PTT. Most COMPREHENSIVE Explanation.


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Bernard-Soulier Syndrome (BSS) is an autosomal recessive (AR) disorder characterized by a defective GP1b platelet receptor leading to a problematic platelet adhesion process (primary hemostasis).

Glanzmann Thrombasthenia (GT) is an autosomal recessive defect in the GPIIb/IIIa (GP2b/3a) receptor on the platelet which leads to defective platelet aggregation.


Ristocetin Cofactor Assay (RIPA) is usually abnormal in cases of Bernard-Soulier Syndrome (BSS).
Bleeding time is prolonged, platelets are big in size, but few in number (Macrothrombocytopenia).

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Platelet count is one of the lab tests used by a doctor or a hematologist to assess whether your platelet number is normal, low (thrombocytopenia) or high (thrombocytosis).

Bleeding 🩸 time (BT) is another test for platelet function.

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