Overview of Immune Dysregulation in Autism – M. Leboyer, Université Paris Est Créteil @Synchrony2020

Описание: Marion Leboyer, M.D., Ph.D. is Professor of Psychiatry at the University of Paris Est (UPEC) in Créteil, France. She is head of the University-affiliated department of Psychiatry (Hôpitaux Universitaires Mondor, Assistance-Publique-Hôpitaux de Paris). She also runs the laboratory “Translational Psychiatry” (http://www.imrb.inserm.fr/equipes/m-l...) which is part of Mondor Institute (Inserm U955).

Since 2007, she is the executive director of a non profit foundation, “Fondation FondaMental” (www.fondation-fondamental.org) created by the French Ministry of Research. Dr. Leboyer has authored or co-authored 480 peer-reviewed international publications (H-factor = 73) on autism spectrum disorder and major affective and psychotic disorder.

Her research efforts contributed to a better identification of genetic and environmental risk factors associated with major psychiatric disorders towards better understanding of causal mechanisms. In particular, she has contributed to the identification of mutations of genes implicated in synaptogenesis in autism, associations of genetic vulnerability factors in bipolar disorders, discovery of immune dysfunctions, environmental risk factors as well as brain imaging abnormalities.

Her goal is to develop diagnostic tools to better identify homogenous subgroups of psychiatric disorders paving the way to mechanisms-based treatments. Within the expert center networks centers created and coordinated by Fondation FondaMental, several cohorts of patients have been followed allowing for the construction of shared observational databases. These networks have enabled multiple collaborations within different national and international research programs.

Dr Leboyer is the principal investigator of several international and national research projects funded by the National Research Agency and by the French Ministry of Health.


#psychiatry #psychiatric #neuroimmune #neuropsychiatric #diagnostics


This talk was part of Synchrony 2020 Online Symposium - 'From Bench to Biopharma', organised in partnership with UC Davis MIND Institute and CalTech. For more Synchrony 2020 talks:    • Synchrony Symposium 2020 - From Bench To B...  


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Synchrony https://synchronysymposium.com/ is the first and only international symposium on translational research in #autism, that brings together academia, #biotech, pharmaceutical companies and #venture partners from around the world with the mission to improve health and quality of life of people with #autismspectrumdisorder

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The BRAIN Foundation https://brainfoundation.org/ is a 501c(3) non-profit. The founders of BRAIN envision a world where every child and adult on the autism spectrum is healthy, participates fully in education and employment, and has a better quality of life. It aims to catalyze research that results in evidence-based interventions for the disabilities associated with autism, and also results in better medical standard of care. To accomplish this, it funds impactful research through #philanthropy and our network of partners in the venture, corporate, and grassroots community.