MYOPIA TREATMENT: Atropine LAMP study: Low Dose Atropine for Myopia Control & Management

Описание: MYOPIA TREATMENT: Atropine LAMP study: Low Dose Atropine for Myopia Control

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This is a summary of the LAMP myopia study: Low-Concentration Atropine for Myopia Progression (LAMP) Study. This study is one of the important studies that establishes what dose of atropine is an effective treatment for myopia control in order to slow the progression of myopia in children.


Link to Journal articles
ATOM1: https://pubmed.ncbi.nlm.nih.gov/16996...
ATOM2: Phase 1: https://pubmed.ncbi.nlm.nih.gov/21963...
ATOM2: Phase 2: https://pubmed.ncbi.nlm.nih.gov/24315...
ATOM2; Phase 3: https://www.aao.org/assets/28fe020e-5...
LAMP Phase 1: https://www.aaojournal.org/article/S0...
LAMP Phase 2: https://www.aaojournal.org/article/S0...


CLINICAL PEARLS:
00:00 Intro
02:44 PEARL 1
03:03 PEARL 2
03:24 PEARL 3
04:13 PEARL 4
04:59 PEARL 5

This study is a called Low-Concentration Atropine for Myopia Progression (LAMP) Study and sometimes it is referred to as the LAMP Study. There are 4 phases to this study phase 1 was published in ophthalmology in January 2019 and phase 2 in July 2020. I’m talking about phase 1 and phase 2 in this study.

PEARL 1: THERE IS A CONCENTRATION DEPENDENT EFFECT ON MYOPIA CONTROL WITH LOW DOSE ATROPINE.

PEARL 2: 0.01% DOESN’T SEEM TO HAVE ANY EFFECT ON AXIAL LENGTH COMPARED TO PLACEBO

Pearl 3: 0.05% is the most effective in controlling myopia and axial length with minimal symptoms over 1 year

PEARL 4: CONCENTRATION DEPENDENT EFFECTS REMAIN IN FIRST 2 YEARS.

PEARL 5: LAMP STUDY PHASE 1 & 2 SHOW THAT 0.05% IS 2X MORE EFFECITVE THAN 0.01% OVER 2 YEARS

So the ATOM 2 study results resulted in an increase in optometrists using 0.01% atropine for myopia management, but the results of the LAMP study have indicated that eye doctors should be using 0.05% atropine one drop in each eye every evening for myopia control

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