3g Balances Cortisol and Increases Deep Sleep within minutes - Dr David Sinclair
Автор: Sinclair Explained
Загружено: 2026-02-18
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What if one simple amino acid could help you detach from stress, improve sleep architecture, and optimize cortisol rhythm?
In this 20-minute deep dive, Dr. David Sinclair explores the overlooked power of glycine — a naturally occurring amino acid with profound effects on sleep quality, autonomic balance, and metabolic health.
You’ll discover how 3 grams before bed can dramatically enhance deep sleep, why 1 gram in the morning may improve stress resilience, and the neuroscience behind glycine’s role as both an inhibitory neurotransmitter and NMDA receptor modulator.
From cortisol regulation to emotional flexibility and circadian rhythm optimization, this video reveals a strategic protocol designed to improve performance, recovery, and long-term health.
If you struggle with sleep, chronic stress, rumination, or poor recovery — this may be the simplest intervention you haven’t tried.
Watch until the end for dosing strategies, timing protocols, and the science behind why glycine works.
🔎 What You’ll Discover
How glycine influences cortisol patterns
The connection between sleep quality and stress resilience
Why emotional “detachment” can improve decision-making
The role of NMDA receptors in stress regulation
The optimal glycine dosing strategy (morning vs night)
How parasympathetic dominance improves metabolic health
Why autonomic flexibility is the key to performance
⏱ Time Stamps
0:00 🧠 Introduction – The Glycine Discovery
1:42 🌙 Why 3g Before Bed Changes Sleep Architecture
3:55 🔬 Glycine as an Inhibitory Neurotransmitter
6:10 ⚡ NMDA Receptors & Stress Modulation
8:05 🕒 Cortisol, Circadian Rhythm & The SCN
10:12 🧘 Emotional Blunting vs Emotional Control
12:40 💪 Autonomic Flexibility & Performance
14:18 🏋️ Why Morning Glycine Enhances Recovery
16:02 🔥 Visceral Fat, Cortisol & Metabolic Health
17:30 🧂 Creatine + Glycine Synergy Explained
18:45 📊 Measured Results & Sleep Score Improvements
19:50 ✅ Complete Glycine Protocol Recap
glycine supplementation, cortisol reduction, stress resilience, sleep optimization, deep sleep improvement, autonomic nervous system balance, parasympathetic activation, emotional regulation, NMDA receptor modulation, circadian rhythm support, sleep latency reduction, slow wave sleep enhancement, brain energy metabolism, creatine synergy, visceral fat reduction, metabolic health optimization, fight or flight response control, recovery enhancement, biohacking sleep, stress management protocol
#Glycine #DavidSinclair #SleepOptimization #StressRelief #CortisolControl #Biohacking #DeepSleep #LongevityScience #AutonomicNervousSystem #NMDA #Parasympathetic #BrainHealth #MetabolicHealth #WellnessProtocol #SupplementScience #FightOrFlight #StressManagement #LongevityTips #HealthOptimization #PerformanceRecovery
💡 POWERFUL VIRAL TOP 5 TIPS
1️⃣ Take 3g glycine 30–60 minutes before bed to enhance deep sleep and reduce nighttime awakenings.
2️⃣ Add 1g in the morning to improve stress resilience and emotional control during high-pressure situations.
3️⃣ Combine glycine with creatine to support brain energy stability and recovery.
4️⃣ Use glycine consistently for 2–4 weeks before evaluating results — sleep architecture adapts gradually.
5️⃣ Track sleep score, morning alertness, and stress reactivity to objectively measure impact.
📚 References
Bannai M et al. “The effects of glycine on subjective daytime performance in partially sleep-restricted subjects.” Frontiers in Neurology (2012).
Inagawa K et al. “Glycine ingestion improves subjective sleep quality.” Sleep and Biological Rhythms (2006).
Yamadera W et al. “Glycine ingestion improves sleep quality in humans.” Sleep and Biological Rhythms (2007).
Basic neuroscience research on NMDA receptor modulation and glycinergic signaling.
Research on cortisol circadian rhythm and autonomic balance.
⚠ Disclaimer
This video is for educational and informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before beginning any supplementation protocol, especially if you are taking medications or have underlying medical conditions. Individual results may vary.
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