Lobular Neoplasia – Brief History & Spectrum of Lesions |

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The term lobular neoplasia refers to both ALH and LCIS. Lobular neoplastic lesions have also been classified using an alternative nomenclature: lobular intraepithelial neoplasia. Lobular neoplastic lesions (ALH and LCIS) are often multicentric and bilateral.1, 18 They occur predominantly in premenopausal women, with most cases being diagnosed in women between 40 and 50 years of age.

The majority of invasive carcinomas that subsequently occur in cases of lobular neoplasia are ductal, no special type. But invasive lobular carcinomas constitute up to 45% of subsequent carcinomas.

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Dr. Maj Gen Reena Bharadwaj, Retd. SM, VSM, Clinical Adviser Lab Services, prof. Sr. Consultant Pathology, Indraprastha Apollo Hospitals, Delhi.

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