How heavy alcohol consumption increases brain inflammation
Автор: Medical Dialogues
Загружено: 2023-03-07
Просмотров: 441
Описание:
For people with alcohol use disorder (AUD), there is a constant, vicious cycle between changes to the brain and changes to behavior. Alcohol use disorder can alter signaling pathways in the brain; in turn, those changes can exacerbate drinking.
Now, scientists at Scripps Research have uncovered new details about the immune system’s role in this cycle. They reported in the journal Brain, Behavior and Immunity, that the immune signaling molecule interleukin 1β is present at higher levels in the brains of mice with alcohol dependence. In addition, this interleukin pathway takes on a different role in these animals, causing inflammation in critical areas of the brain known to be involved in decision-making.
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