Klebsiella Oxytoca; Definition, Key features, Pathogenicity, Virulence factors, Treatment

Описание: Klebsiella oxytoca is a gram-negative, rod-shaped bacterium closely related to Klebsiella pneumoniae. Here are some key points about this bacterium:

Characteristics
Gram-negative: K. oxytoca is a gram-negative, rod-shaped bacterium.

Indole-positive: It is distinguished from K. pneumoniae by being indole-positive.

Growth Characteristics: It can grow on melezitose but not on 3-hydroxybutyrate.

Habitat and Isolation
Environmental Source: K. oxytoca is commonly found in the intestinal tract, mouth, and nose. It can also be present in soil and water.

Clinical Relevance: It is an opportunistic pathogen that can cause infections, particularly in healthcare settings.

Infections
K. oxytoca can cause a variety of infections, including:

Pneumonia: It can cause pneumonia-like symptoms.

Urinary Tract Infections (UTIs): It can lead to UTIs, especially in individuals with catheters.

Wound Infections: It can cause wound infections, particularly in hospitalized patients.

Colitis and Sepsis: Infections can result in colitis and sepsis.

Antibiotic Resistance
K. oxytoca has a high tendency to develop antibiotic resistance, making infections difficult to treat. Some strains produce extended-spectrum beta-lactamases (ESBLs) and carbapenemases, which confer resistance to a wide range of antibiotics

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