The Lost Evolutionary Synthesis

Описание: Do genes matter in evolutionary biology?

In this lecture, we confront this odd question by telling the story of a forgotten branch of evolutionary theory. You'll meet a whole cast of characters you've never heard of before, and be introduced to the most practical subfield in biology - quantitative genetics.

Timestamps
0:00 - Do genes matter?
4:10 - Wendel Mitchell Levi & The Pigeon
13:34 - Mendelian genetics
33:56 - Who was Francis Galton?
42:17 - Regression to the mean
48:59 - Law of Ancestral Heredity
56:44 - Who was Karl Pearson?
59:25 - Statistical selection theory
1:06:27 - Fisher (1918) & Deriving the infinitesimal model
1:35:00 - Implications of the infinitesimal model
1:40:40 - Jay Lush & Animal Breeding Plans
1:50:04 - Unifying population and quantitative genetics
1:56:20 - Efficiency of selection in the infinitesimal regime
2:01:20 - Conclusion

References
Barton, N. (2022) https://www.pnas.org/doi/abs/10.1073/...
Tautz, D. et al. (2026) https://academic.oup.com/genetics/adv...
Boyle, E.A. et al. (2017) https://www.cell.com/cell/fulltext/S0...
Barton, N. et al. (2017) https://www.sciencedirect.com/science...
Hledick, M. et al. (2022) https://www.pnas.org/doi/abs/10.1073/...
Fisher, R.A. (1918) http://l.academicdirect.org/Horticult...
Robertson, A. (1960) https://royalsocietypublishing.org/rs...
Pigeon genetics: https://learn.genetics.utah.edu/conte...
Nick Barton on the infinitesimal:    • Fisher 1918 paper symposium - Nick Barton ...  
Subhadra Das on Galton:    • Subhadra Das and the many thoughts of Fran...  
Fisher's fundamental theorem:    • Deriving Fisher's Theorem: The Math Behind...