The impact of TP53 mutations and copy number loss on survival outcomes in patients with LBCL
Автор: VJHemOnc – Video Journal of Hematology & HemOnc
Загружено: 2025-07-18
Просмотров: 185
Описание:
Daniel Landsburg, MD, University of Pennsylvania, Philadelphia, PA, comments on the impact of TP53 alterations on the prognosis of patients with newly diagnosed large B-cell lymphoma (LBCL) treated with standard frontline chemotherapy. Dr Landsburg summarizes a study that found TP53 mutations, copy number loss, and the combination of both predicted for inferior two-year progression-free survival. This interview took place during the 18th International Conference on Malignant Lymphoma (18-ICML) in Lugano, Switzerland.
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