UK CEiRSI Airlock Panel: In Silico Models in Radiotherapy

Описание: UK CEiRSI In Silico Regulatory Airlock Panel Session:
In-device integration of treatment data and models for optimised radiotherapy performance

About UK CEiRSI:
The UK’s first Centre of Excellence in In-Silico Regulatory Science and Innovation (UK CEiRSI) advances computational evidence in healthcare, bringing together academia, industry, and regulators to shape global standards.

About the In Silico Regulatory Airlock Panel Sessions:
These sessions bring together individuals from academia, industry, and regulatory bodies, to examine the practical strengths and weaknesses of existing international credibility frameworks. Each Case Study Panel Session will focus on a hypothetical medical intervention (drug or device) that will enable us to interrogate and refine current standards and frameworks for the credibility assessment of model-informed evidence.

About this Case Study:
Aim: To establish credibility recommendations for in-silico models in radiotherapy by evaluating whether integrating treatment data, device logs, imaging, and radiobiology models can predict the impact of device variations on patient safety, as measured by tumour control probability and normal tissue complication probability, to inform quality assurance and regulatory compliance.

Agenda:
Rationale for the use of in-silico radiobiology models for radiotherapy treatment systems
Panel credibility recommendations for the credibility assessment of in-silico radiobiology models
Panel and audience Q&A

Case Study Leads:
Dr Tuathan O’Shea, Varian
David Grainger, MHRA
Prof Derek Hill, University College London

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Connect with the InSilico UK Community:
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