Accelerate Antibody Discovery with HT Kinetic Screening of Phage Libraries | Carterra LSA Platform

Описание: Distributed Bio’s phage display library has been computationally optimized based on the analysis of thousands of human antibody repertoires. Their library routinely produces over 5000 unique antibodies against any target.

How do they efficiently screen so many unique hits? They use the Carterra platform.

The Carterra LSA Array SPRi platform is the only antibody screening technology that can deliver high quality kinetic data directly from scFv bacterial supes at a high enough throughput to meet capacity, enabling thousands of clones to be screened in just days. This gives Distributed Bio the confidence to bypass ELISA screening and proceed directly to binding kinetics and epitope binning after panning. Combining Distributed Bio’s phage display library with Carterra’s LSA, enables bioengineering feats that make many other discovery technologies obsolete and can help you achieve a one-week discovery cycle.

Learning Objectives:
Learn how Array SPRi accelerates kinetic screening of your antibody library by orders of magnitude
Survey the epitope landscape of your antibody library at the earliest stages of discovery
Identify unique epitopes while retaining epitope diversity
Build your IP portfolio

Speakers:
Jacob Glanville, PhD
Co-Founder and Chief Science Officer
Distributed Bio

Yasmina Noubia Abdiche, PhD
Chief Science Officer
Carterra