Part-1। Pharmaceutical organic chemistry 2nd semester important questions। Short & long Questions।

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Today In this video I provide Pharmaceutical organic chemistry-1 (POC-1) B Pharm 2nd semester important questions : Short & long questions with solution pdf. (Part-1)


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Unit-I
Classification, Nomenclature and Isomerism: Classification of Organic Compounds,
Common and IUPAC systems of nomenclature of organic compounds (up to 10 Carbons open chain and carbocyclic compounds). Structural isomerism in organic compounds.


Unit II
Alkanes*, Alkenes* and Conjugated dienes*
sp3 hybridization in alkanes, Halogenation of alkanes, uses of paraffins. Stabilities of
alkenes, sp2 hybridization in alkenes.
E1 and E2 reactions – Kinetics, order of reactivity of alkyl halides, rearrangement of
carbocations, Saytzeff’s orientation and evidences. E1 verses E2 reactions, Factors
affecting E1 and E2 reactions. Ozonolysis, electrophilic addition reactions of alkenes,
Markownikoff’s orientation, free radical addition reactions of alkenes, Anti-
Markownikoff’s orientation.
Stability of conjugated dienes, Diel-Alder, electrophilic addition, free radical addition
reactions of conjugated dienes, allylic rearrangement.

Unit III
Alkyl halides*
SN1 and SN2 reactions - kinetics, order of reactivity of alkyl halides, stereochemistry
and rearrangement of carbocations. SN1 versus SN2 reactions, Factors affecting SN1 and SN2 reactions.
Structure and uses of ethyl chloride, chloroform, trichloroethylene, tetrachloroethylene, dichloromethane, tetrachloromethane and iodoform.
Alcohols*- Qualitative tests, Structure and uses of Ethyl alcohol, Methyl alcohol,
chlorobutanol, Cetosteryl alcohol, Benzyl alcohol, Glycerol, Propylene glycol.

Unit-IV
Carbonyl compounds* (Aldehydes and ketones)Nucleophilic addition, Electromeric effect, aldol condensation, Crossed Aldol
condensation, Cannizzaro reaction, Crossed Cannizzaro reaction, Benzoin condensation,
Perkin condensation, qualitative tests, Structure and uses of Formaldehyde, Paraldehyde, Acetone, Chloral hydrate, Hexamine, Benzaldehyde, Vanillin, Cinnamaldehyde.


Unit-V
Carboxylic acids*: Acidity of carboxylic acids, effect of substituents on acidity,
inductive effect and qualitative tests for carboxylic acids, amide and ester.
Structure and Uses of Acetic acid, Lactic acid, Tartaric acid, Citric acid, Succinic acid.
Oxalic acid, Salicylic acid, Benzoic acid, Benzyl benzoate, Dimethyl phthalate, Methyl
salicylate and Acetyl salicylic acid.
Aliphatic amines*: Basicity, effect of substituent on Basicity. Qualitative test,
Structure and uses of Ethanolamine, Ethylenediamine, Amphetamine.