Mechanism of Action of Insulin

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Video Summary:
Insulin receptors are receptors tyrosine kinase. Upon activation, first there will be cross phosphorylation of tyrosine residues. Then IRS protein is recruited and phosphorylated. There are two main pathways downstream of this. PI3K pathway that leads to changes in the metabolism of glucose and protein and MAPK pathway that increases gene expression and growth.

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DISCLAIMER: This video is for education purposes only. Although every effort is made to ensure the accuracy of the material, viewers should refer to the appropriate regulatory body/authorized websites, guidelines, and other suitable sources of information as deemed relevant and applicable. In view of the possibility of human error or changes in medical science, any person or organization involved in the preparation of this work accepts no responsibility for any errors or omissions, or results obtained from the use of information in this video.