Kleihauer-Betke Test | How to Detect Fetal Maternal Hemorrhage?

Описание: The Kleihauer-Betke (KB) test is a blood test used during pregnancy to screen maternal blood for the presence of fetal red blood cells when Rh negative mother conceives Rh positive baby.
It is mainly used to assess the severity of a fetomaternal hemorrhage (FMH), a condition in which a disruption in the placental barrier allows fetal blood to enter the maternal circulation.
The conditions causing fetomaternal hemorrhage include Miscarriage or threatened miscarriage. A blood sample from the mother is made into a smear on a glass slide, then the slide is flooded with acid. The mother RBCs from which the hemoglobin has been washed out are now called GHOST CELLS. But the fetal cells will remain the same. The number of fetal cells is then counted to estimate the total volume of fetal blood.
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