Structural Database of Allergenic Proteins (SDAP) | Lecture 77 | Dr. Muhammad Naveed

Описание: Structural Database of Allergenic Proteins (SDAP)
weblink: https://fermi.utmb.edu/SDAP/index.html

SDAP is a Web server that integrates a database of allergenic proteins with various computational tools that can assist structural biology studies related to allergens. SDAP is an important tool in the investigation of the cross-reactivity between known allergens, in testing the FAO/WHO allergenicity rules for new proteins, and in predicting the IgE-binding potential of genetically modified food proteins. Using this Internet service through a browser, it is possible to retrieve information related to an allergen from the most common protein sequence and structure databases (SwissProt, PIR, NCBI, PDB), to find the sequence and structural neighbors for an allergen, and to search for the presence of an epitope other the whole collection of allergens.

SDAP is a Web server that integrates a database of allergenic proteins with various bioinformatics tools for performing structural studies related to allergens and characterization of their epitopes.

The SDAP project is supported by grants from the National Institute of Health (2R56AI064913), and the U.S. Environmental Protection Agency under a STAR Research Assistance Agreement (No. RD 834823).

SDAP database:
1526 Allergens and isoallergens: List
1312 Protein sequences for allergens and isoallergens: List
92 Allergens with PDB structures: List
458 3D models for allergens and isoallergens: List
29 Allergens with IgE epitope sets: List
130 Pfam allergen classes: List

SDAP computational tools:
Go! FAO/WHO Allergenicity Test
Go! Search your protein with FASTA against all SDAP allergens
Go! Search your epitope (peptide) for exact matches in all SDAP allergens
Go! Search your epitope (peptide) for similar regions in all SDAP allergens, using our original PD sequence similarity index
Go! Compute the PD sequence similarity index for two sequences provided by the user
For any epitope in SDAP, search for exact matches in the PIR (Protein Information Resources) database
For any epitope in SDAP, search for similar regions in all SDAP allergens, using our original PD sequence similarity index
For any epitope in SDAP, search for exact matches in all SDAP allergens

About Dr. Muhammad Naveed
(Associate Professor, Biotechnology, University of Central Punjab, Lahore)
With distinction, Dr. Muhammad Naveed obtained a Ph.D. degree in Biotechnology (Genomics & Bioinformatics) from Quaid-e-Azam University, Islamabad. He has won Ph.D. indigenous & IRSIP scholarships from HEC. He has done Pre-Doc research at the University of Ghent, Belgium. HEC awarded him the best Ph.D. (IRSIP) Scholar of the year in 2013 & QAU honored him as a “Distinguished Alumni” in 2017. He is doing research projects in Bioinformatics, Molecular Biotechnology & Vaccine designing, and Drug designing against infectious diseases. He has supervised 70 MSc. and 60 MPhil. & 01 Ph.D. students. He has published 102 Research articles with 504 impact factors, 1850 citations, 01 book, and 03 book chapters. He has been awarded the distinguished “Researcher of the Year” in 2016 (UoG) and 2018, 2019 & 2021 (UCP).
#SDAP #allergens #database