Patrizia D’Alessio: Targeting Inflammation & Gut Barrier Repair for Healthy Longevity | LSD 2025
Автор: Longevity Summit Dublin
Загружено: 2025-08-11
Просмотров: 437
Описание:
Dr. Patrizia D’Alessio shares decades of research into endothelial biology, inflammation, and aging. She presents a plant-derived monoterpene that acts as a biophysical regulator to inhibit pro-inflammatory signaling, repair the gut barrier, rebalance the microbiome, and even modulate mood through dopamine pathways. The talk covers molecular mechanisms, first-in-human results, and implications for cardiometabolic disease prevention and skin health.
Chapters:
00:00 Introduction – Inflammation & aging
01:05 Endothelial cells & immune cell recruitment
02:33 Cytoskeleton control of inflammation
04:58 Discovery of a plant-derived anti-inflammatory molecule
07:11 Mechanism of action – Rho inhibition
09:19 First-in-human studies – inflammation markers & gut health
12:37 Gut barrier repair & microbiome modulation
14:45 Dopamine pathways & mood improvement
16:45 Lifestyle, vagal activation & resilience
18:39 Skin health applications & quality of life
#Inflammaging #GutHealth #LongevityScience #HealthyAging #Microbiome #longevitysummitdublin
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