“Understanding Shock: The Receptor Level Logic Behind Vasopressor Choices”
Автор: Beyond The Prescription
Загружено: 2026-02-15
Просмотров: 16
Описание:
Hi..
This is Dr. Sarath Nandanavanam MBBS MD Pharmacologist, India.
Vasopressors and inotropes are routinely used in casualty and ICU settings — but the pharmacological reasoning behind their selection is often reduced to simplified algorithms.
In this discussion, we explore the receptor-level logic and physiological nuances behind the use of:
• Norepinephrine
• Dobutamine
• Dopamine
• Vasopressin
We compare their roles in cardiogenic shock and septic shock, focusing on:
• Alpha-1, Beta-1 and V1 receptor physiology
• Why norepinephrine is first-line in septic shock
• When dobutamine truly adds value
• The diminishing role of dopamine
• The rationale for vasopressin as an adjunct
• Hemodynamic subtleties often missed in routine practice
This is not a comprehensive lecture.
It is a reflective discussion on the clinical reasoning that often guides critical care decisions.
Intended for doctors and healthcare professionals
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