Purine and Pyrimidine Disorders for USMLE and COMLEX: What Builds Up and Why It Matters
Автор: Pediatric Board Review
Загружено: 2026-02-06
Просмотров: 7
Описание:
Purine and pyrimidine disorders are best understood through cause-and-effect thinking, not memorization. In this video, we review what purines and pyrimidines are, how they become nucleotides, and what happens when key enzymes are missing.
We cover high-yield disorders such as orotic aciduria and adenosine deaminase deficiency, including their relationship to hyperammonemia and SCID, and how USMLE and COMLEX signal these diagnoses.
Purine and pyrimidine disorders made simple for USMLE Step 1, COMLEX Level 1, and Pediatric Board Review. Stop confusing Lesch-Nyhan, orotic aciduria, and adenosine deaminase deficiency.
These disorders come up on every board exam, and most students get tripped up because they try to memorize them as isolated diseases. This video gives you a simple framework: what builds up, what breaks down, and how to match the disease to the defect every time.
We'll cover:
The synthesis vs. salvage vs. degradation framework
How to instantly distinguish purine from pyrimidine disorders on an exam
Lesch-Nyhan, ADA deficiency, and orotic aciduria — the 3 you must know
🔗 Subscribe for more high-yield pediatric and biochemistry review.
#Purines #Pyrimidines #USMLE #COMLEX #Biochemistry #LeschNyhan #Pediatrics #Step1 #BoardReview
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